Pharmaceuticals
Developing and supplying
pharmaceutical ingredients
that contribute to
the health of the people.
Business Overview
Supplier of Critical Pharmaceutical Ingredient Material and Excipients
In the area of pharmaceutical excipients, we provide NISSO HPC (hydroxypropyl cellulose) and NISSO SSF (sodium stearyl fumarate).
NISSO HPC is a binder that is used in the formulation of pharmaceuticals,and NISSO SSF is used as a lubricant.
Both products are highly appreciated for their functionality and safety and widely used in the pharmaceutical industry.
The safety and superior functionality of NISSO HPC and NISSO SSF are most suitable excipients for OD tablets (Orally disintegrating tablets in pharmaceutical products).
In recent years, the demand for OD tablets, which are an easy-to-swallow dosage form for patients who have difficulty swallowing, the elderly, and children who have difficulty taking regular tablets, has been increasing. Synergies between the excellent binding strength and water solubility of NISSO HPC and the hydrophilic properties of NISSO SSF allow us to design OD tablet formulations that combine the contradictory properties of tablet hardness and disintegration.
Main Products
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Pharmaceutical and food excipients
NISSO HPC
NISSO HPC (hydroxypropyl cellulose) is primarily used as a binding agent (pharmaceutical additive) for molding pharmaceutical tablets.
Being one of few additives that dissolve in water and alcohol, it is widely used as an indispensable additive in the manufacture of pharmaceuticals because it can impart high functionality to pharmaceutical products, such as binding strength to increase tablet hardness and sustained release properties to gradually release active ingredients.
For example, its high binding strength makes it possible to create smaller tablets, its excellent sustained release properties reduce the number of doses of a drug needed, and it maintains a constant blood concentration of the drug’s active ingredients.
Under the name “CELNY”, it has been increasingly used in supplements and other food products. Its high binding strength makes it possible to create formulations with many natural materials that are difficult to mold, thereby reducing the number and frequency of supplements taken. -
Pharmaceutical excipient
NISSO SSF
NISSO SSF (sodium stearyl fumarate) is a lubricant (pharmaceutical additive) in the production of tablets. It is primarily used in tableting and dry granulation as a means of preventing tablet failure. The presence of hydrophilic groups in the molecule improves the disintegration time of tablets, making it suitable for use in orally disintegrating (OD) tablets. Its low activity also makes it suitable for use with active ingredients in pharmaceuticals. Using NISSO SSF as a lubricant can suppress the effects of over-mixing tableting powder on tablets’ physical properties, making it suitable for the continuous pharmaceutical production technology that has been gaining attention in recent years.
Product List
| Products | NISSO HPC/CELNY (Hydroxypropyl Cellulose) | NISSO SSF (Sodium Stearyl Fumarate) | NISSO DAMN (Diaminomaleonitrile) |
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